MOG is a transmembrane protein expressed on the surface of oligodendrocyte cell and on the outermost surface of myelin sheaths. MOG comprises about 0.1% of total CNS myelin protein. The MOG gene is a member of the immunoglobulin gene superfamily and is found within the MHC. The MOG gene is found on chromosome 6p21.3-p22. Myelin Oligodendrocyte Glycoprotein is a glycoprotein thought to be significant in the process of myelinization of nerves in the central nervous system （CNS）. MOG peptide （35-55） is highly encephalitogenic and can induce strong T and B cell responses. A single injection of this peptide produces a relapsing- remitting neurologic disease with extensive plaque-like demyelination. Because of the clinical， histophathologic， and immunologic similarities with multiple sclerosis （MS）， the MOG induced demyelinating encephalomyelitis may serve as a model for investigating MS.
Sterile Filtered White lyophilized （freeze-dried） powder. The protein was lyophilized with no additives. It is recommended to reconstitute the lyophilized MOG in sterile 18MΩ-cm H2O not less than 100ug/ml， which can then be further diluted to other aqueous solutions.
保存建议
Lyophilized MOG although stable at room temperature for 3 weeks， should be stored desiccated below -18℃. Upon reconstitution MOG should be stored at 4℃ between 2-7 days and for future use below
-18℃.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles.
