TCF20 (Transcription Factor 20) is a Protein Coding gene. Diseases associated with TCF20 include Vertebrobasilar Insufficiency and Breast Sarcoma. Among its related pathways are Human Embryonic Stem Cell Pluripotency and PAK Pathway. TCF20 encodes a transcription factor that recognizes the platelet-derived growth factor-responsive element in the matrix metalloproteinase 3 promoter. The encoded protein is thought to be a transcriptional coactivator, enhancing the activity of transcription factors such as JUN and SP1. Mutations in TCF20 are associated with autism spectrum disorders. Alternative splicing results in multiple transcript variants.
