PLCH2 (Phospholipase C Eta 2) is a Protein Coding gene. Diseases associated with PLCH2 include Chromosome 1P36 Deletion Syndrome. Among its related pathways are Phospholipase-C Pathway and Metabolism. PLCH2 is a member of the PLC-eta family of the phosphoinositide-specific phospholipase C (PLC) superfamily of enzymes that cleave PtdIns(4,5) P2 to generate second messengers inositol 1,4,5-trisphosphate and diacylglycerol .