CNGB3 (Cyclic Nucleotide Gated Channel Beta 3) is a Protein Coding gene. Diseases associated with CNGB3 include Achromatopsia 3 and Stargardt Disease 1. Among its related pathways are Nanog in Mammalian ESC Pluripotency and Activation of cAMP-Dependent PKA. CNGB encodes the beta subunit of a cyclic nucleotide-gated ion channel. The encoded beta subunit appears to play a role in modulation of channel function in cone photoreceptors. This heterotetrameric channel is necessary for sensory transduction, and mutations in this gene have been associated with achromatopsia 3, progressive cone dystrophy, and juvenile macular degeneration, also known as Stargardt Disease.
