KCNK9(potassium two pore domain channel subfamily K member 9) encodes a protein that contains multiple transmembrane regions and two pore-forming P domains and functions as a pH-dependent potassium channel. Amplification and overexpression of KCNK9 have been observed in several types of human carcinomas. KCNK9 is imprinted in the brain, with preferential expression from the maternal allele. A mutation in KCNK9 was associated with Birk-Barel mental retardation dysmorphism syndrome. Alternative splicing results in multiple transcript variants.基因ID为:51305;蛋白质ID:Q9NPC2