AASS encodes a bifunctional enzyme (aminoadipate-semialdehyde synthase)that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in AASS are associated with familial hyperlysinemia. 蛋白别名为:AASS; Alpha-aminoadipic semialdehyde synthase; mitochondrial; LKR/SDH;基因ID为:10157;蛋白质ID:Q9UDR5
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:10000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human AASS. at AA rangle: 220-300