Glutathione S-transferase (GSTs) theta 2 (GSTT2) is a
member of a superfamily of proteins that catalyze the conjugation
of reduced glutathione to a variety of electrophilic and
hydrophobic compounds. Human GSTs can be divided into five main
classes: Alpha, Mu, Pi, Theta, and Zeta. The theta class members
GSTT1 and GSTT2 share 55% amino acid sequence identity and both are
thought to have an important role in human carcinogenesis. The
theta genes have a similar structure, being composed of five exons
with identical exon/intron boundaries.
