Transmembrane protein 204 (TMEM204) is a four-transmembrane protein that is induced under hypoxic conditions. It localizes to cell-cell junctions and co-localizes with the beta-catenin adherens junction-associated protein, but not with tight junctions. Overexpression of TMEM204 results in decreased adhesion between cells, indicating that TMEM204 is an adherens junction protein that modulates cell adhesion and potentially angiogenesis. Recent evidence suggests TMEM204 may also be involved in epilepsy.
Anti-TMEM204 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide near the C-terminus of human TMEM204.
来源宿主
Rabbit
反应性
H. sapiens (Human); Mus musculus (Mouse); Rattus (Rat)
保存建议
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
