HSPB8 is part of the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. HSPB8 is induced by estrogen in estrogen receptor-positive breast cancer cells. HSPB8 protein functions as a chaperone in association with BAG3， a stimulator of macroautophagy. HSPB8 participates in the regulation of cell proliferation， apoptosis， and carcinogenesis. Mutations in HSPB8 gene have been related with different neuromuscular diseases， including Charcot-Marie-Tooth disease.
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来源宿主
大肠杆菌中重组表达
溶解建议
Sterile Filtered colorless solution. The HSPB8 protein solution contains 20mM Tris-HCl pH-8， 100mM NaCl， and 10% glycerol.
保存建议
HSPB8 although stable 4℃ for 4 weeks， should be stored desiccated below -18℃. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Please prevent freeze-thaw cycles.
