Cyclin B2 is a member of the cyclin family, specifically
the B-type cyclins. The B-type cyclins, B1 and B2, associate with
p34cdc2 and are essential components of the cell cycle regulatory
machinery. B1 and B2 differ in their subcellular localization.
Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is
primarily associated with the Golgi region. Cyclin B2 also binds to
transforming growth factor beta RII and thus cyclin B2/cdc2 may
play a key role in transforming growth factor beta-mediated cell
cycle control.
