Translin is a DNA and RNA binding protein that identifies specifically preserved target sequences at the breakpoint junction of chromosomal translocations. TSN forms a ring-shaped configuration， that is in charge of DNA binding， and in addition has a leucine zipper motif， which is believed to assist TSN to form dimers. TSN exports specific mRNAs out of the nucleus， reinforced by its localization in both the nuclei and cytoplasm of neurons， and regulates their translation.
