Kruppel-Like Factor 7 （KLF7） is a part of the Kruppel-like transcriptional regulator family whose members regulate cell proliferation， differentiation and survival and contain 3 C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. KLF7 contributes to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and also by deregulating adipocytokine secretion in adipocytes.
