RHOQ （rho-related GTP-binding protein RhoQ） is a small signaling G protein which cycles between an active GTP-bound and an inactive GDP-bound state. In the active state it binds to a diversity of effector proteins to regulate cellular responses. Ras-like protein belongs to the Rac subfamily of the Rho family of GTPases. RHOQ is involved in epithelial cell polarization processes. In addition， RHOQ plays a role in CFTR trafficking to the plasma membrane. RHOQ causes the formation of thin， actin-rich surface projections called filopodia.
