Carcinoembryonic antigen (CEA) is one of the most commonly used tumor markers in serum immunoassay determinations of carcinoma. Members of the CEACAM (carcinoembryonic antigen-related cell adhesion molecule) family contain a single N domain, with structural homology to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant- like A and/or B domains. CEACAM21 (carcinoembryonic antigen-related cell adhesion molecule 21) is a 293 amino acid single-pass type I membraneprotein that belongs to the CEACAM family and contains one Ig-like C2-type domain. CEACAM21 exists as three alternatively spliced isoforms that areencoded by a gene which maps to human chromosome 19.
来源宿主
Carcinoembryonic antigen (CEA) is one of the most commonly used tumor markers in serum immunoassay determinations of carcinoma. Members of the CEACAM (carcinoembryonic antigen-related cell adhesion molecule) family contain a single N domain, with structural homology to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant- like A and/or B domains. CEACAM21 (carcinoembryonic antigen-related cell adhesion molecule 21) is a 293 amino acid single-pass type I membraneprotein that belongs to the CEACAM family and contains one Ig-like C2-type domain. CEACAM21 exists as three alternatively spliced isoforms that areencoded by a gene which maps to human chromosome 19.
