The product of MAP1LC3B is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for MAP1LC3B in autophagy, a process that involves the bulk degradation of cytoplasmic component. MAP1LC3B (Microtubule Associated Protein 1 Light Chain 3 Beta) is a Protein Coding gene. Diseases associated with MAP1LC3B include Spastic Paraplegia 49, Autosomal Recessive and Sporadic Pheochromocytoma. Among its related pathways are Cellular Senescence (REACTOME) and Vesicle-mediated transport.
