Cleobopride maleate is a substituted benzamide compound and dopamine receptor antagonist that is related to metoclopramide.1,2 Initial studies of the blockade of cerebral dopamine receptors indicated that cleobopride showed greater activity compared to metoclopramide.3 Incubation of rabbit liver homogenates with cleobopride resulted in the formation of the metabolites 4-amino-5-chloro- 2-methoxybenzoic acid and N-(4'-piperidyl)-4- amino-5-chloro-2-methoxybenzamide.4Alternate Name:4-(4-Amino-5-chloro-2-methoxybenzamido)-1-benzylpiperidine; Clebopride Malate; 4-amino-5-chloro-2-methoxy-N-[1-(phenylmethyl) 4-piperidinyl]benzamideCAS Number:57645-91-7,84370-95-6Molecular Formula:C20H24ClN3O2·C4H6O5Molecular Weight:507.96Purity:≥98%Appearance:Supplied as a white to off-white powderLoss on Drying:≤1%Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
