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ELISA试剂盒
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中文名称

Aspergillus fumigatus IgG ELISA试剂盒 (Human)

英文名字
Aspergillus fumigatus IgG ELISA Kit (Human)
供应商
Aviva Systems Biology
产品货号
aviva-OKNA00103-96W
产品报价
¥询价/96Wells
产品说明书
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背景资料
Aspergillus fumigatus is a fungus of the genus Aspergillus, and is one of the most common Aspergillus species to cause disease in individuals with an immunodeficiency.
A. fumigatus, a saprotroph widespread in nature, is typically found in soil and decaying organic matter. Colonies of the fungus produce thousands of small conidia (2-3 um) that readily become airborne. The fungus is capable of growth at temperatures up to 50 C, with conidia surviving at 70 C. Humans are continuously in contact with these asexual spores and it is estimated that an individual inhales several hundred conidia each day; typically these are quickly eliminated by the immune system.
Aspergillosis develops mainly in individuals who are immunocompromised, either from disease or from immunosuppressive drugs, and is a leading cause of death in acute leukemia and hematopoietic stem cell transplantation.
The term aspergillosis comprises a number of different diseases caused by fungi of the genus Aspergillus. The most common forms are allergic bronchopulmonary aspergillosis (ABPA), pulmonary aspergilloma and invasive aspergillosis (IA).
Allergic bronchopulmonary aspergillosis is characterized by an exaggerated response of the immune system to Aspergillus species. It occurs in patients suffering from asthma or cystic fibrosis. Clinically, ABPA manifests as a bronchial asthma with transient pulmonary infiltrates that may proceed to proximal bronchiectasis and lung fibrosis.
Aspergilloma, commonly referred to as “fungus ball,” occurs in preexisting pulmonary cavities that were caused by tuberculosis, sarcoidosis, or other bullous lung disorders. The fungus settles in a cavity and grows until it forms a compact sphere, which incorporates dead tissue from the surrounding lung, mucus, and other debris. Patients are usually asymptomatic and often coexist for decades with aspergillomae prior to incidental diagnosis. However, it may cause hemoptysis.
Invasive aspergillosis is a rapidly progressive, often fatal disease, targeting severely immunocompromised patients, including those with hematological malignancies such as leukemia, those who have received solid organ or hematopoietic stem cell transplants, and individuals with chronic granulomatous disease or advanced AIDS. IA is characterized by invasion of blood vessels, resulting in multifocal infiltrates. Dissemination to other organs, particularly the central nervous system, may occur.
产品描述
该Aspergillus fumigatus IgG ELISA Kit (Human)的产品描述请参考该产品的说明书
产品特点
ELISA试剂盒
保存建议
Store as indicated in product manual.
其他
Aviva Systems Biology总部位于加利福尼亚州圣迭戈,在中国北京设有办公室,专注于为研究需求提供多克隆和单克隆抗体、ELISA试剂盒、蛋白质和定制服务。Aviva Systems Biology生产了24,000种经过验证的多克隆抗体,并提供近20,000种ELISA试剂盒,定制实验室服务包括蛋白表达和纯化、抗体开发,以及ELISA的开发、验证和生产。Aviva Systems Biology为与独特物种和靶标相关的研究提供独特工具,研究领域包括转录因子、癌症、心血管、细胞生物学、DNA损伤和修复、表观遗传学、信号转导、细胞分化、干细胞生物学等等。
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