ATF-6 is a member of the basic-leucine zipper family of transcription factors. Endoplasmic reticulum stress causes cleavage of transmembrane ATF-6 and transclocation of active ATF-6 to the nucleus. Soluble ATF-6 can exist as either an ATF-6β homodimer or an ATF-6α/β heterodimer. Binding of the ATF-6β homodimer or ATF-6α/β heterodimer to the nuclear transcription factor Y C (NF-YC) induces ER chaperone transcription.
应用类型
WB,IF
免疫原
Recombinant full length Human ATF6.
来源宿主
该ATE1产品的来源宿主详情查看产品说明书。
反应性
rabbit
保存建议
该Rabbit IgG polyclonal antibody for Cyclic AMP-dependent transcription factor ATF-2(ATF2) detection. Tested with WB, IHC, IHC-F, FCM in Human;Mouse;Rat.产品的保存建议详情查看产品说明书。
