CK2 (formerly called Casein Kinase II) is a highly conserved protein kinase with more than 300 substrates regulating cell growth, cell death, and cell survival. CK2 has been implicated in the response to UV irradiation-induced DNA damage, targeting XRCC1 and BRCA1 as well as regulating p53 tumor suppressor protein functions.Furthermore, CK2 plays a key role in NF-κB activation.
应用类型
WB
免疫原
Synthetic phosphopeptide derived from human Cytokeratin 8 around the phosphorylation site of Serine 432
