- 中文名称
ATG14
- 英文名字
- ATG14
- 供应商
- Nordic BioSite
- 产品货号
- NDC-BT-KFVDPS-100
- 产品报价
- ¥询价/100ul

- 产品说明书
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- 购买方式
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- 产品新闻

- 背景资料
- Atg14 (ATG14 autophagy related 14 homolog), also known as BARKOR (beclin 1-associated autophagy-related key regulator) or ATG14L, is a 492 amino acid protein that contains 3 coiled-coil domains in its N-terminal region. Conserved in chimpanzee, canine, bovine, mouse, rat, chicken, zebrafish, fruit fly and mosquito, Atg14 exhibits highest expression in brain and lowest expression in kidney and ovary. Atg14 localizes to isolation membranes of forming autophagosomes, cytoplasm, endoplasmic reticulum and an uncharacterized punctate structure. Necessary for both basal and inducible autophagy, Atg14 plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine. Atg14 promotes BECN1 translocation from the trans-Golgi network to autophagosomes, and forms a complex with BECN1, PI 3-kinase p100 and p150. Atg14 does not form complexes with KIAA0226/Rubicon or UVRAG, which forms a mutually exclusive complex with BECN1 through direct competition with Atg14.
- 应用类型
- WB,IHC
- 免疫原
- Recombination protein, corresponding to amino acids 152-406 of Human ATG14.
- 来源宿主
- rabbit
- 反应性
- human,mouse,rat
- 保存建议
- Store at 4
- 其他
- Nordic BioSite(北欧生物) 总部位于瑞典,成立于1997年,旨在分销研究和诊断领域的高质量和创新产品。 Nordic BioSite 被公认为整个北欧生物医学研究和诊断产品领域的领导者。他们拥有超过570万种的产品组合,代理了遍布欧洲和美国的顶级生物试剂制造商,是欧洲知名的一站式生物试剂代理商。除了作为分销商之外,Nordic BioSite 还拥有不断增长的自产产品线——BioSite mAb、BioSite ELISA、BioSite Flow、Optibodies和 BioSite Protein, 目前艾美捷代理的是Nordic BioSite自产产品线(共26W+产品)。Nordic BioSite的产品类型主要是抗体,蛋白和试剂盒,产品适用范围涵盖15个不同的物种(人,牛,犬,鲶鱼,鸡,海豚,马,猫,豚鼠,小鼠,绵羊,兔子,大鼠,猪和火鸡),可为您提供一站式的生命科学研究解决方案~

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