CD48 is a glycosylphosphatidylinositol (GPI) -anchored membrane protein of the signaling lymphocyte activation molecule (SLAM) family, also known as SLAMF2 and BLAST-1. It is constitutively expressed on most hematopoietic cells (not on neutrophils and a subset of long-term hematopoietic stem cells in mice) and can be upregulated under certain conditions like infection. Interaction with its low affinity ligand CD2 promotes adhesion and TCR signaling. Interaction with the high affinity ligand CD244 (2B4) regulates natural killer (NK) and CD8 T cell activation and cytolytic function.
应用类型
该CD48 Recombinant Protein产品的应用类型详情查看产品说明书。
免疫原
该CD48 Recombinant Protein产品的免疫原详情查看产品说明书。
来源宿主
bacteria
反应性
该Rabbit IgG polyclonal antibody for CD47 detection. Tested with WB, IHC, FCM, Direct ELISA in Human.产品的反应性详情查看产品说明书。
