Androgen receptor (AR), a zinc finger transcription factor belonging to the nuclear receptor superfamily, is activated by phosphorylation and dimerization upon ligand binding. This promotes nuclear localization and binding of AR to androgen response elements in androgen target genes. Research studies have shown that AR plays a crucial role in several stages of male development and the progression of prostate cancer.
应用类型
该AR产品的应用类型详情查看产品说明书。
免疫原
Synthetic peptide, corresponding to Human AR.
来源宿主
rabbit
反应性
该Mouse Monoclonal Antibody to ANAPC10产品的反应性详情查看产品说明书。
