This gene encodes a metal-binding membrane glycoprotein that oxidatively deaminates putrescine, histamine, and related compounds. The encoded protein is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
应用类型
IF,WB
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human AOC1 (NP_001082.2).
