PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2014]
应用类型
该Mouse Monoclonal Antibody to PAX2产品的应用类型详情查看产品说明书。
免疫原
Purified recombinant fragment of human PAX2 (AA: 194-304) expressed in E. Coli.
来源宿主
该Mouse Monoclonal Antibody to NTRK3产品的来源宿主详情查看产品说明书。
