NRXN1 (Neurexin 1) is a Protein Coding gene. Diseases associated with NRXN1 include Pitt-Hopkins-Like Syndrome 2 and Schizophrenia 17. Among its related pathways are Muscular Dystrophies and Dystrophin-Glycoprotein Complex and Cell adhesion molecules (CAMs). NRXN1 encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca(2+)-dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission and is involved in the formation of synaptic contacts.
