Succinyladenosine (S-Ado) is a biochemical marker of adenylosuccinase deficiency - the genetic defect of purine de novo synthesis. S-Ado has been previously reported as normally undetectable in cerebrospinal fluid (CSF) of children not suffering from this defect.Synonyms: N-(9-B-D-Ribofuranosyl-9H-purin-6-yl)-L-aspartic Acid; 6-(1,2-Dicarboxyethylamino)-9-B-D-ribofuranosylpurine; (S)-N-(1,2-Dicarboxyethyl)adenosine; SuccinoadenosineCAS No: 4542-23-8Molecular Formula: C14H17N5O8Molecular Weight: 383.31Appearance: Supplied as a white solid.Purity: ≥95%Melting Point: >180ºC (dec)Solubility: DMSO (slightly), Methanol (slightly)Method for Determining Identity:Proton NMR (DMSO-d6) Spectroscopic and Mass Spectrometric AnalysisTLC Conditions:C18; Acetonitrile: Water = 8:2; Visualized with UV and AMCS; SIngle spot, Rf=0.70Specific Rotation:-29ºC (c=0.3, Methanol)Storage and Stability:May be stored at RT for short-term only. Long-term storage is recommended at -20°C. Stable for 6 months after receipt.. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
