TRIM21 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. Ro/SSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Ribonucleoprotein particle is composed of a single polypeptide and one of four small RNA molecules. The RoSSA is present in all mammalian cells studied but has no known function. At least 2 isoforms are present in nucleated and red blood cells, and tissue specific differences in Ro/SSA proteins were identified.
序列
该TRIM21 Protein的序列请参考该产品的说明书
来源宿主
该TRIM21 Protein的来源宿主请参考该产品的说明书
溶解建议
该TRIM21 Protein的溶解建议请参考该产品的说明书
保存建议
该TRIM21 Protein的保存建议请参考该产品的说明书
其他
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