The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.
序列
该EIF2AK3 Recombinant Protein (Human)的序列请参考该产品的说明书
来源宿主
E. Coli
溶解建议
该EIF2AK3 Recombinant Protein (Human)的溶解建议请参考该产品的说明书
保存建议
该EIF2AK3 Recombinant Protein (Human)的保存建议请参考该产品的说明书
其他
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