Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA (By similarity).
序列
该SEMA4D Recombinant Protein的序列请参考该产品的说明书
来源宿主
E.coli
溶解建议
该SEMA4D Recombinant Protein的溶解建议请参考该产品的说明书
保存建议
该SEMA4D Recombinant Protein的保存建议请参考该产品的说明书
其他
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