Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modulates down-stream signaling. Promotes activation of down-stream protein kinases, including STAT3, AKT1, MAPK1 and/or MAPK3. Promotes activation of HRAS. Plays a role in signal transduction in response to EGF. Plays a role in the regulation of cell proliferation and cell migration (By similarity). Plays a role in the assembly and stability of RNA stress granules. Binds to the 5'UTR of target mRNA molecules and represses translation of target mRNA species, when not phosphorylated. Phosphorylation impairs RNA binding and promotes stress granule disassembly during recovery after cellular stress.
序列
该GRB7 Recombinant Protein的序列请参考该产品的说明书
来源宿主
E.coli
溶解建议
该GRB7 Recombinant Protein的溶解建议请参考该产品的说明书
保存建议
该GRB7 Recombinant Protein的保存建议请参考该产品的说明书
其他
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