May act as a link between RND2 signaling and regulation of the actin cytoskeleton (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during the late stage of clathrin-mediated endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also enhances actin polymerization via the recruitment of WASL/N-WASP, which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. May be required for the lysosomal retention of FASLG/FASL.
序列
该FNBP1 Recombinant Protein的序列请参考该产品的说明书
来源宿主
E.coli
溶解建议
该FNBP1 Recombinant Protein的溶解建议请参考该产品的说明书
保存建议
该FNBP1 Recombinant Protein的保存建议请参考该产品的说明书
其他
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