PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for serine/threonine-protein phosphatase 2A (PP2A) modulating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg(2+) (By similarity). Reversibly stimulates the variable phosphotyrosyl phosphatase activity of PP2A core heterodimer PP2A(D) in presence of ATP and Mg(2+) (in vitro). The phosphotyrosyl phosphatase activity is dependent of an ATPase activity of the PP2A(D):PPP2R4 complex. Is involved in apoptosis; the function appears to be independent from PP2A.
序列
该PPP2R4 Recombinant Protein (Human)的序列请参考该产品的说明书
来源宿主
该PPP2R4 Recombinant Protein (Human)的来源宿主请参考该产品的说明书
溶解建议
该PPP2R4 Recombinant Protein (Human)的溶解建议请参考该产品的说明书
保存建议
该PPP2R4 Recombinant Protein (Human)的保存建议请参考该产品的说明书
其他
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