With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator.
序列
该Nus1 Recombinant Protein的序列请参考该产品的说明书
来源宿主
Mouse
溶解建议
该Nus1 Recombinant Protein的溶解建议请参考该产品的说明书
保存建议
该Nus1 Recombinant Protein的保存建议请参考该产品的说明书
其他
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