- 中文名称
Angiotensin I ELISA试剂盒
- 英文名字
- Angiotensin I ELISA Kit
- 供应商
- Aviva Systems Biology
- 产品货号
- aviva-OKEH02621-96W
- 产品报价
- ￥询价/96Wells
- 产品说明书
- 点击查看
- 购买方式
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- 产品新闻
- 背景资料
- Angiotensins are small peptides derived from angiotensinogen. Several of the known Angiotensins are established endocrine effectors in the regulation of blood pressure, but they are also known to have other functions locally, in several organs and tissues (paracrine) and at the cellular level (autocrine / intracrine). Angiotensin I has no known effector function but it is an immediate precursor of Angiotensin II. Angiotensin II binds AT1 receptors, which promote vasoconstriction, sodium retention, release of aldosterone, release of Argâ€Âvasopressin, cell proliferation, inflammation, fibrosis, anxiety, and cardiac hypertrophy. Angiotensin A and Angiotensin III, also bind AT1 receptors. Angiotensin (1â€Â7) binds a different receptor called MASâ€Â1 which has opposite effects (vasodilation, natriuresis, antiproliferation, NO release, PGE release, and apoptosis). Angiotensin IV binds yet another receptor called AT4 (IRAP), which promotes increase of blood flow, angiogenesis, and natriuresis, and which has also been implicated in memory formation and in the pathogenesis of Alzheimer’s disease. The peptide LVVâ€Âhemorphinâ€Â7, which is not an angiotensin, also binds the AT4 receptor. There are other angiotensin peptides that Discover more at www.abcam.com 3 INTRODUCTION have been identified, including Ang (1â€Â9), Ang (1â€Â12), Ang V(3â€Â7), as well as several other shorter peptides that have undetermined functions. Angiotensins can be present in very low concentrations in some biological samples. In such cases, dilution of samples to avoid “nonâ€Âspecific†interference by any present factors is not productive because the angiotensin analyte is also diluted to levels far below the minimum detection concentration. Thus, investigators have used several procedures for extracting Angiotensins from biological samples prior to using them for immunoassays. Angiotensins share common sequences, and in some cases they cannot be discriminated by immunoassays. Prior extraction and separation by HPLC may, thus, be required.
- 产品描述
- 该Angiotensin I ELISA Kit的产品描述请参考该产品的说明书
- 产品特点
- ELISA试剂盒
- 保存建议
- Store as indicated in product manual.
- 其他
- Aviva Systems Biology总部位于加利福尼亚州圣迭戈，在中国北京设有办公室，专注于为研究需求提供多克隆和单克隆抗体、ELISA试剂盒、蛋白质和定制服务。Aviva Systems Biology生产了24,000种经过验证的多克隆抗体，并提供近20,000种ELISA试剂盒，定制实验室服务包括蛋白表达和纯化、抗体开发，以及ELISA的开发、验证和生产。Aviva Systems Biology为与独特物种和靶标相关的研究提供独特工具，研究领域包括转录因子、癌症、心血管、细胞生物学、DNA损伤和修复、表观遗传学、信号转导、细胞分化、干细胞生物学等等。
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- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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