Synapsin I plays a key role in synaptic plasticity in brain (Feng et al., 2002; Nayak et al., 1996). This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation (Jovanovic et al., 2001; Kao et al., 2002). Ser 549 along with Ser 62 and Ser 67 are the sites of synapsin I that are phosphorylated by MAP kinase (Jovanovic et al., 1996). Phosphorylation and subsequent dephosphorylation of this site is thought to play a key role in synaptic vesicle trafficking.
应用类型
WB, IHC
免疫原
Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser549 of synapsin I.
来源宿主
Rabbit
反应性
该Synapsin I 抗体 (Phospho-Ser549)的反应性请参考该产品的说明书
保存建议
Store at -20C; stable for at least one year.
其他
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