Synaptobrevin (aka VAMP) is an integral membrane protein of synaptic vesicles that plays a major role in the formation of larger SNARE complexes, along with SNAP-25 and syntaxin. Synaptobrevin has been shown to be essential for two fast synapse-specific membrane trafficking processes: fast exocytosis for neurotransmitter release and fast endocytosis that mediates rapid recycling of synaptic vesicles (Deak et al., 2004). Decreased levels of synaptobrevin in human hippocampus and cortex have been correlated with cognitive defects in Alzheimer's disease (Sze et al., 2000).
应用类型
WB, IHC
免疫原
Synaptic immunoprecipitate (crude) from human brain.
来源宿主
Mouse
反应性
该Anti-Synaptobrevin (VAMP)的反应性请参考该产品的说明书
保存建议
Store at -20C; stable for at least one year.
其他
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