- 中文名称
SMAD7 抗体 - C-末端区域
- 英文名字
- SMAD7 Antibody - C-terminal region
- 供应商
- Aviva Systems Biology
- 产品货号
- aviva-OABB01103-100UG
- 产品报价
- ￥询价/100ug
- 产品说明书
- 点击查看
- 购买方式
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- 产品新闻
- 背景资料
- SMAD7(Mother against decapentaplegic drosophila homolog of 7), also known as MADH7 or SMA- AND MAD-RELATED PROTEIN 7, is a protein that in humans is encoded by the SMAD7 gene. It belongs to the SMAD family of proteins, which belong to the TGFbeta superfamily of ligands. By somatic cell hybrid analysis, Topper et al.(1997) mapped the MADH7 gene to human chromosome 18. Topper et al.(1997) demonstrated that MADH7 and MADH6 could form complexes in endothelial cells. MADH7 was induced in cultured vascular endothelium by fluid mechanical forces and was capable of modulating endothelial gene expression in response to both humoral and biomechanical stimuli in vitro. By FISH, Roijer et al.(1998) refined the localization to 18q21.1. Lallemand et al.(2001) showed that cells stably expressing SMAD7 had increased susceptibility to apoptosis induced by TGFB, TNFA, serum withdrawal, or loss of cell adhesion.
- 应用类型
- WB, IHC-P
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human MADH7(375-389aa YSLQRPNDHEFMQQP), identical to the related rat and mouse sequences.
- 来源宿主
- Rabbit
- 反应性
- Human, Rat
- 保存建议
- Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.. At -20C for one year from date of receipt. After reconstitution, at 4C for one month. It can also be aliquotted and stored frozen at -20C for six months. Avoid repeated freezing and thawing.
- 其他
- Aviva Systems Biology总部位于加利福尼亚州圣迭戈，在中国北京设有办公室，专注于为研究需求提供多克隆和单克隆抗体、ELISA试剂盒、蛋白质和定制服务。Aviva Systems Biology生产了24,000种经过验证的多克隆抗体，并提供近20,000种ELISA试剂盒，定制实验室服务包括蛋白表达和纯化、抗体开发，以及ELISA的开发、验证和生产。Aviva Systems Biology为与独特物种和靶标相关的研究提供独特工具，研究领域包括转录因子、癌症、心血管、细胞生物学、DNA损伤和修复、表观遗传学、信号转导、细胞分化、干细胞生物学等等。
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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