- 中文名称
A晶状体蛋白B抗体
- 英文名字
- Alpha B Crystallin Antibody: Dylight 488
- 供应商
- StressMarq
- 产品货号
- SPC-126B-DY488
- 产品报价
- ￥已停产
- 产品说明书
- 点击查看
- 购买方式
- StressMarq中国区现货中心已经建立，90%产品中国有现货库存。银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- The A-crystallins are major water-soluble lens structural proteins of the vertebrate eye that are related to the small heat shock protein family. The A-crystallins possess structural and functional similarities with HSP25 and HSP27 (1). Mammalian lens cystallins are divided into A, B and gamma families. A and B families are further divided into acidic and basic groups (A-A and A-B respectively). In the lens, A-crystallin primarily functions to maintain proper refractive index, however it can also function as a molecular chaperone that binds to the denatured proteins, keeping them in solution and thereby maintaining the translucency of the lens. When cellular stress occurs, A-crystallin enters its’ phosphorylated state and may serve a structural control function and play a role in protein maintenance (2). In addition to their interaction with proteins, A-crystallins also interact with native molecules such as membrane proteins, Golgi matrix protein, structural proteins, nuclear proteins and DNA (3, 4, 5, 6, and 7). Two other functions are an autokinase activity and participation in the intracellular architecture, and it has also been proven that both A-A and B prevent apoptosis by inhibiting caspases (8). Specifically, A-B cystallin is found in many cells and organs outside the lens, and A B is overexpressed in several neurological disorders and in cell lines under stress conditions (9).
- 应用类型
- WB | IHC | ICC/IF
- 免疫原
- 人A晶状体蛋白B合成肽, 钥孔虫戚血蓝素螯合.
- 来源宿主
- 兔
- 反应性
- 人 | 小鼠 | 大鼠 | 牛 | 鸡
- 保存建议
- 厂家推荐蓝冰运输。收到产品后建议保存于-20ºC。
- 其他
- StressMarq Biosciences Inc. 在2007年成立于加拿大维多利亚，是一家生物科技公司，专门从事试剂与试剂盒研究，服务范围遍及2635多个国家。 StressMarq公司的核心技术领域为细胞应激（尤其是热休克蛋白（HSP）领域，领先全球），离子通道，载体研究，同时在神经科学领域推出特有的具有生物活性的Tau蛋白与A-突触核蛋白。产品领域涉及到：细胞凋亡、细胞信号、通路和转运、细胞器标志物、热休克、神经生物学、神经科学、氧化应激、磷酸化运输等。除了提供用于进一步研究的相关工具外，Str
- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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