- 中文名称
血管内皮生长因子受体1 抗体
- 英文名字
- VEGF Receptor 1 Antibody: Dylight 488
- 供应商
- StressMarq
- 产品货号
- SPC-1210D-DY488
- 产品报价
- ￥已停产
- 产品说明书
- 点击查看
- 购买方式
- StressMarq中国区现货中心已经建立，90%产品中国有现货库存。银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-2777
- 产品新闻
- 背景资料
- FLT1 is a receptor-tyrosine kinase that is activated upon binding with VEGF-A, VEGF-B and PGF. It plays an important role in the development of embryonic vasculature, and as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. However, it can promote PGF-mediated endothelial cell proliferation, survival and angiogenesis in adults, although this seems to be cell-type specific. It also contributes to cancer cell survival, proliferation, migration, and invasion, as well as tumour angiogenesis, metastasis, and recruitment of tumour-infiltrating macrophages. It has a very high affinity for VEGF-A and may function as a negative regulator of VEGF-A signalling by limiting the amount of free VEGF-A and preventing its binding to KDR. Isoforms lacking a transmembrane domain may function as decoy receptors for VEGF-A. Furthermore, it mediates phosphorylation of PI3K, leading to activation of the downstream signalling pathway, as well as mediating the activation of the MAPK signalling pathway, and of the Akt/PKB signalling pathway.
- 应用类型
- WB | AM
- 免疫原
- 人 VEGF Receptor 1 (AA143-158)合成肽
- 来源宿主
- 兔
- 反应性
- 人 | 小鼠
- 保存建议
- 厂家推荐蓝冰运输。收到产品后建议保存于-20ºC。
- 其他
- StressMarq Biosciences Inc. 在2007年成立于加拿大维多利亚，是一家生物科技公司，专门从事试剂与试剂盒研究，服务范围遍15899多个国家。 StressMarq公司的核心技术领域为细胞应激（尤其是热休克蛋白（HSP）领域，领先全球），离子通道，载体研究，同时在神经科学领域推出特有的具有生物活性的Tau蛋白与A-突触核蛋白。产品领域涉及到：细胞凋亡、细胞信号、通路和转运、细胞器标志物、热休克、神经生物学、神经科学、氧化应激、磷酸化运输等。除了提供用于进一步研究的相关工具外，Str
- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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