ZFAND3 holds a DNA-binding domain and has a large number of purposes， most of which include certain form of transcriptional activation or repression. ZFAND3 is a 251 aa protein having two AN1-type zinc fingers and two UIM （ubiquitin-interacting motif） repeats. The AN1-type zinc finger domain is conserved in animals and plants and is frequently found in proteins which hold an ubiquitin-like domain， which proposes a part in the ubiquitination pathway.
