CD69 is a disulfide linked transmembrane homodimer whose differentially glycosylated subunits range from 35-39 kDa. It is a C type lectin, most closely related to the NKRP1 and Ly49 NK cell activation molecules. CD69 is involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. It is the earliest inducible cell surface glycoprotein acquired during lymphoid activation. Induction occurs by antigens, mitogens or activators of PKC on the surface of T and B lymphocytes, and by interaction of IL2 with the p75 IL2R on the surface of NK cells. Constitutive expression of CD69 on subsets of thymocytes suggests that it may be involved in regulation of developmental events in addition to its role in activation of a variety of hematopoietic cells.
应用类型
WB
免疫原
Recombinant full length Human CD69.
来源宿主
该Anti-Hu CD51/CD61 Purified产品的来源宿主详情查看产品说明书。
反应性
rabbit
保存建议
该Rabbit IgG polyclonal antibody for CD68 detection. Tested with IHC, Direct ELISA in Human.产品的保存建议详情查看产品说明书。
