- 中文名称
CD111/NECTIN1 Recombinant Protein
- 英文名字
- CD111/NECTIN1 Recombinant Protein
- 供应商
- Nordic BioSite
- 产品货号
- NDC-BT-XUPUXL-1
- 产品报价
- ¥询价/1mg

- 产品说明书
- 点击查看
- 购买方式
- 90%产品中国有现货库存。银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868
- 产品新闻

- 背景资料
- Nectin is a Ca2+-independent homophilic cell adhesion molecule that belongs to the immunoglobulin superfamily. Human Nectin is identical to the poliovirus receptor-related protein (PRR) and is identified to be the α herpesvirus entry mediator. Nectin constitutes a family consisting of at least Nectin 1, 2 and 3. Nectin 2 and 3 are ubiquitously expressed, whereas Nectin 1 is abundantly expressed in the brain. Nectin 1 exists as Nectin 1α and 1β/HIgR, produced by alternative splicing. The cytoplasmic regions of Nectin 1α, but not Nectin 1β/ HIgR, have a C-terminal conserved motif (E/A-X-Y-V). This motif interacts with the PDZ domain of the F-Actin-binding protein, afadin, through which it is linked to the Actin cytoskeleton. Nectin 1, also designated HveC/ PRR1, allows the entry of herpes simplex virus type 1 (HSV-1) and HSV-2 into mammalianncells. The interaction of virus envelope glycoprotein D (gD) with Nectin 1 is an essential step in the process leading to membrane fusion; the gD binding site is located at the first Ig-like domain of Nectin 1. Both the transinteraction of Nectin and the interaction of Nectin with afadin are necessary for their co-localization with E-cadherin and catenins at adherens junctions.
- 应用类型
- 该CD111/NECTIN1 Recombinant Protein产品的应用类型详情查看产品说明书。
- 免疫原
- 该CD111/NECTIN1 Recombinant Protein产品的免疫原详情查看产品说明书。
- 来源宿主
- bacteria
- 反应性
- 该Rabbit polyclonal to DPYSL3产品的反应性详情查看产品说明书。
- 保存建议
- Store at 4
- 其他
- Nordic BioSite(北欧生物) 总部位于瑞典,成立于1997年,旨在分销研究和诊断领域的高质量和创新产品。 Nordic BioSite 被公认为整个北欧生物医学研究和诊断产品领域的领导者。他们拥有超过570万种的产品组合,代理了遍布欧洲和美国的顶级生物试剂制造商,是欧洲知名的一站式生物试剂代理商。除了作为分销商之外,Nordic BioSite 还拥有不断增长的自产产品线——BioSite mAb、BioSite ELISA、BioSite Flow、Optibodies和 BioSite Protein, 目前艾美捷代理的是Nordic BioSite自产产品线(共26W+产品)。Nordic BioSite的产品类型主要是抗体,蛋白和试剂盒,产品适用范围涵盖15个不同的物种(人,牛,犬,鲶鱼,鸡,海豚,马,猫,豚鼠,小鼠,绵羊,兔子,大鼠,猪和火鸡),可为您提供一站式的生命科学研究解决方案~

- 注意
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