Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
应用类型
WB
免疫原
Recombinant protein of human CAPN9
来源宿主
该Calcitonin产品的来源宿主详情查看产品说明书。
反应性
rabbit
保存建议
该Mouse IgG monoclonal antibody for Calpain 2 detection. Tested with WB, IHC, ICC/IF, FCM in Human;Mouse;Monkey.产品的保存建议详情查看产品说明书。
