AF10 is a putative transcription factor containing a leucine zipper motif. A t (10;11) (p12;q23) chromosomal translocation present in a proportion of acute myeloid leukaemias results in expression of an AF10 (carboxy terminus) MLL (amino terminus) fusion protein.
应用类型
IHC,IF
免疫原
Synthetic peptide, corresponding to amino acids 200-250 of Human AF-10.