The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq]
应用类型
该DOK2产品的应用类型详情查看产品说明书。
免疫原
Full length human recombinant protein of human DOK2(NP_003965) produced in HEK293T cell.
