Aurora kinases belong to a highly conserved family of mitotic serine/threonine kinases with three members identified among mammals: Aurora A, B, and C. Studies on the temporal expression pattern and subcellular localization of Aurora kinases in mitotic cells suggest an association with mitotic structure. Aurora kinase functional influences span from G2 phase to cytokinesis and may be involved in key cell cycle events such as centrosome duplication, chromosome bi-orientation and segregation, cleavage furrow positioning, and ingression.
应用类型
该AURKB/C (phospho-T236/202)产品的应用类型详情查看产品说明书。
免疫原
Synthetic phosphopeptide derived from human AURKB/C around the phosphorylation site of Threonine 236/202.
