Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation, Additional complex functions may be a consequence of its influence on mRNA expression, Is not required for association of CNOT7 to the CCR4-NOT complex.
应用类型
WB
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 465-744 of human CNOT10 (NP_056257.1).