Required for proper alignment of chromosomes at metaphase and their accurate segregation during mitosis, Involved in the maintenance of spindle microtubules attachment to the kinetochore during sister chromatid biorientation, May recruit CENPE and CENPF to the kinetochore.
应用类型
IF,IHC,WB
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 563-812 of human CHAMP1 (NP_115812.1).