Sialomucin that may play a key role in hematopoiesis by facilitating the adhesion of CD34(+) cells to the stroma and by negatively regulating CD34(+)CD38(lo/-) cell proliferation, Modulates the migration of umbilical cord blood CD133+ cells and this is mediated through the CXCL12/CXCR4 axis, May play an important role in prostate cancer metastasis and the infiltration of bone marrow by cancer cells, Promotes myogenesis by enhancing CXCR4-dependent cell motility, Positively regulates myoblast migration and promotes myoblast fusion into myotubes (By similarity).
应用类型
WB
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 24-162 of human CD164 (NP_006007.2).