This gene encodes a coiled-coil domain-containing protein. The encoded protein functions as a receptor for ubiquitin-coated bacteria and plays an important role in innate immunity by mediating macroautophagy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
应用类型
WB
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 137-446 of human CALCOCO2 (NP_005822.1).